Intimacy
Kisspeptin
10mg
$41.25$55.00
The Collection
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✦Third-party tested✦American made✦Ships in 24–48h
Intimacy
Oxytocin
$33.75$45.00
Strength · 10mg
Oxytocin is a nonapeptide studied extensively for its role in neuroendocrine-signaling research.
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- 5+ vials — 5% · 10+ vials — 10% preferred rate
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Research Notice
For laboratory research use only. Not for human consumption.
The Dossier
Research Notes
Oxytocin is a cyclic nonapeptide hormone and neuropeptide — the first polypeptide hormone ever sequenced and synthesized, accomplished by Vincent du Vigneaud in 1953. It is produced in hypothalamic neurons and differs from vasopressin by only two amino acids.
It is a foundational reference standard in the cognitive category, studied extensively for neuroendocrine-signaling across a range of models.
Research Focus
- ✦Neuroendocrine and social-behavior models
- ✦Smooth-muscle and cardiovascular signaling
- ✦Metabolic-regulation models
- ✦Neuropsychiatric-signaling research
- ✦Addiction and craving models
Mechanism
Oxytocin acts primarily through the oxytocin receptor, a rhodopsin-type G-protein-coupled receptor whose high-affinity state depends on magnesium and cholesterol. Its dominant pathway proceeds through Gαq/11 and phospholipase C to calcium release and PKC signaling.
Secondary pathways characterized in the literature include MAPK/Rho-kinase, PI3K/Akt/eNOS, and inhibitory Gi/Go signaling; the receptor is also reported to form heterodimers with several related receptors.
Molecular Profile
- Sequence
- Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂ (Cys¹–Cys⁶ disulfide)
- Molecular formula
- C43H66N12O12S2
- Molecular weight
- 1007.19 g/mol
- CAS number
- 50-56-6
Storage & Handling
Store refrigerated at 2–8°C, protected from light; activity is documented to decline at body temperature. Handle with standard laboratory PPE.
References
- du Vigneaud V, et al. The sequence of amino acids in oxytocin, with a proposal for the structure. J Biol Chem. 1953.
- Gimpl G, Fahrenholz F. The oxytocin receptor system: structure, function, and regulation. Physiol Rev. 2001.
✦Every vial ships with third-party HPLC verification; certificates of analysis are available on request.
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