Intimacy Research
Kisspeptin 10mg
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99.488% · Kovera Labs · 2026-06-17Report KVR-2026-9D9257 · 10mg
For research use only — not for human or animal use.
Intimacy
PT-141
$50.00
Strength · 10mg
PT-141 is a melanocortin-receptor agonist researched for its central signaling characteristics.
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Research Notice
For laboratory research use only. Not for human consumption.
The Dossier
Research Notes
PT-141 is a cyclic heptapeptide and a metabolite of the melanocortin agonist melanotan II. Unlike its parent, it acts through central melanocortin receptors rather than the pigmentation pathway.
It is studied as a reference standard in the melanocortin-signaling literature, of particular interest in neuroendocrine and functional-health models.
Research Focus
- Melanocortin-receptor (MC4R/MC3R) signaling models
- Central neuroendocrine-pathway research
- Functional and libido-behavior models
- Hypothalamic signaling studies
Mechanism
PT-141 is characterized as an agonist at melanocortin receptors — principally MC4R and MC3R — expressed in hypothalamic and central-nervous-system tissue. Signaling proceeds through Gαs, adenylyl cyclase and cAMP, a pathway distinct from vascular mechanisms.
Molecular Profile
- Sequence
- Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-OH
- Molecular formula
- C50H68N14O10
- Molecular weight
- 1025.2 g/mol
- CAS number
- 189691-06-3
- Also known as
- PT-141, melanocortin-receptor agonist (melanotan II metabolite)
Storage & Handling
Store lyophilized at −20°C, protected from light. Reconstituted solution is held at 2–8°C and used within one to two weeks; avoid repeated freeze-thaw. Handle with standard laboratory PPE.
References
- Molinoff PB, et al. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003.
- Shadiack AM, et al. Melanocortins in the treatment of male and female sexual dysfunction. Curr Top Med Chem. 2007.
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