Intimacy
Kisspeptin
10mg
$41.25$55.00
The Collection
Front
✦Third-party tested✦American made✦Ships in 24–48h
Intimacy
PT-141
$33.75$45.00
Strength · 10mg
PT-141 is a melanocortin-receptor agonist researched for its central signaling characteristics.
1
- Bulk
- 5+ vials — 5% · 10+ vials — 10% preferred rate
- Shipping
- Complimentary US shipping over $200
- Payment
- Card · Zelle · Venmo · Cash App
✦
✦
✦
Research Notice
For laboratory research use only. Not for human consumption.
The Dossier
Research Notes
PT-141 (bremelanotide) is a cyclic heptapeptide and a metabolite of the melanocortin agonist melanotan II. Unlike its parent, it acts through central melanocortin receptors rather than the pigmentation pathway.
It is studied as a reference standard in the melanocortin-signaling literature, of particular interest in neuroendocrine and functional-health models.
Research Focus
- ✦Melanocortin-receptor (MC4R/MC3R) signaling models
- ✦Central neuroendocrine-pathway research
- ✦Functional and libido-behavior models
- ✦Hypothalamic signaling studies
Mechanism
PT-141 is characterized as an agonist at melanocortin receptors — principally MC4R and MC3R — expressed in hypothalamic and central-nervous-system tissue. Signaling proceeds through Gαs, adenylyl cyclase and cAMP, a pathway distinct from vascular mechanisms.
Molecular Profile
- Sequence
- Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-OH
- Molecular formula
- C50H68N14O10
- Molecular weight
- 1025.2 g/mol
- CAS number
- 189691-06-3
- Also known as
- Bremelanotide, PT-141
Storage & Handling
Store lyophilized at −20°C, protected from light. Reconstituted solution is held at 2–8°C and used within one to two weeks; avoid repeated freeze-thaw. Handle with standard laboratory PPE.
References
- Molinoff PB, et al. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003.
- Diamond LE, et al. An effect on the subjective sexual response in premenopausal women with sexual arousal disorder by bremelanotide. J Sex Med. 2006.
✦Every vial ships with third-party HPLC verification; certificates of analysis are available on request.
Continue Exploring
