Longevity Research
Epithalon 40mg
40mg
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly), the synthetic analog of the pineal-gland extract epithalamin, developed at the…
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99.177% · Kovera Labs · 2026-06-23Report KVR-2026-AF5592 · 1500mg
For research use only — not for human or animal use.
Longevity
GLUTATHIONE
$110.00
Strength · 1500mg
Glutathione is a tripeptide antioxidant researched for its central role in cellular redox-balance and detoxification models.
1
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- 5+ vials — 5% · 10+ vials — 10% preferred rate
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Research Notice
For laboratory research use only. Not for human consumption.
The Dossier
Research Notes
Glutathione is a naturally occurring, water-soluble tripeptide of glutamate, cysteine, and glycine, distinguished by an unusual gamma-peptide linkage that protects it from most peptidases. Synthesized in the cytosol of virtually all mammalian cells, it is regarded in the literature as a principal intracellular redox buffer.
It is a foundational reference standard in the longevity category, studied for its central role in redox-balance and detoxification models.
Research Focus
- Redox-balance and oxidative-stress models
- Hepatoprotection models
- Dermatological and skin-research models
- Metabolic-syndrome models
- Detoxification and conjugation research
Mechanism
Glutathione acts not through a single receptor but as a pervasive redox modulator, enzyme cofactor, and post-translational modifier — reversibly forming mixed disulfides on protein cysteines, serving as electron donor for glutathione peroxidases, and conjugating electrophiles via glutathione S-transferases.
It is characterized as regulating the Keap1–Nrf2 antioxidant pathway and NF-κB signaling, with the GSH:GSSG ratio indexing cellular redox status.
Molecular Profile
- Sequence
- γ-Glu-Cys-Gly
- Molecular formula
- C10H17N3O6S
- Molecular weight
- 307.32 g/mol
- CAS number
- 70-18-8
- Also known as
- L-Glutathione, GSH
Storage & Handling
Store the dry powder at −20°C or 2–8°C, where it is stable long-term. Reconstituted solution is aliquoted immediately and protected from light and air; avoid freeze-thaw cycles.
References
- Ballatori N, et al. Glutathione dysregulation and the etiology and progression of human diseases. Biol Chem. 2009.
- Richie JP, et al. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. Eur J Nutr. 2015.
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