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Adamax 30mg
30mg
Adamax is a synthetic analog of the heptapeptide Semax, modified by N-terminal acetylation and C-terminal amidation — adjustments made to…
$115.00
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Cognitive
DSIP
$60.00
Strength · 10mg
Delta Sleep-Inducing Peptide is researched for its role in models of circadian and neuroregulatory signaling.
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Research Notice
For laboratory research use only. Not for human consumption.
The Dossier
Research Notes
Delta Sleep-Inducing Peptide is an amphiphilic nonapeptide first isolated in 1974 from the cerebral venous blood of animals in slow-wave sleep. It is notable for having no definitively identified precursor gene and no cloned dedicated receptor despite decades of study, and is often described as a 'programming modulator' with a bell-shaped concentration-response.
It is a specialized reference in cognitive study, characterized for its behavior across endocrine and central-nervous-system pathways.
Research Focus
- Sleep-regulation models (slow-wave / delta sleep)
- Stress-adaptation and HPA-axis models
- Withdrawal-syndrome models
- Antinociception research
- Neuroprotection and cardioprotection models
Mechanism
With no cloned receptor, DSIP is characterized as interacting across multiple systems — including NMDA-receptor modulation, opioid-receptor activity, and α1-adrenergic engagement associated with pineal signaling.
It is reported to modulate MAPK/ERK signaling and to stimulate antioxidant enzymes while stabilizing mitochondrial oxidative phosphorylation.
Molecular Profile
- Sequence
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE)
- Molecular weight
- 848.8 Da
- CAS number
- 62568-57-4
- Also known as
- Delta Sleep-Inducing Peptide
Storage & Handling
Store the lyophilized peptide at −20°C (or −80°C for longer terms); it is hygroscopic, so protect from moisture. Hold reconstituted solution frozen; the peptide is sensitive to aminopeptidase degradation.
References
- Kovalzon VM, Strekalova TV. Delta sleep-inducing peptide (DSIP): a still unresolved riddle. J Neurochem. 2006.
- Graf MV, Kastin AJ. Delta-sleep-inducing peptide (DSIP): a review. Neurosci Biobehav Rev. 1984.
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