Metabolic
5-Amino 1MQ
50mg
$56.25$75.00
The Collection
Front
✦Third-party tested✦American made✦Ships in 24–48h
Metabolic
Cagrilintide
$90.00$120.00
Strength · 10mg
Composition & control — single-batch, third-party verified.
1
- Bulk
- 5+ vials — 5% · 10+ vials — 10% preferred rate
- Shipping
- Complimentary US shipping over $200
- Payment
- Card · Zelle · Venmo · Cash App
✦
✦
✦
Research Notice
For laboratory research use only. Not for human consumption.
The Dossier
Research Notes
Cagrilintide is a long-acting, acylated analog of human amylin, engineered from the amylin scaffold with a fatty-diacid chain and anti-fibrillation substitutions that give it a multi-day half-life. It functions as a dual amylin- and calcitonin-receptor agonist.
It is a distinctive reference within the metabolic category, studied for its role in satiety-signaling and receptor-pharmacology models.
Research Focus
- ✦Satiety- and energy-balance models
- ✦Metabolic and glycemic-control models
- ✦Amylin/calcitonin receptor pharmacology
- ✦Combination-signaling research
- ✦Structural-biology (receptor cryo-EM) research
Mechanism
Cagrilintide is characterized as a non-selective dual agonist of calcitonin receptors and amylin receptors — the latter being calcitonin-receptor/RAMP heterodimers. Receptor engagement activates Gs, adenylyl cyclase, and cAMP as the primary satiety-signaling cascade.
It is reported to bind via a receptor conformation with short residence time, characterized as limiting receptor desensitization.
Molecular Profile
- Molecular weight
- ≈4409 Da
- CAS number
- 1415456-99-3
- Also known as
- AM833, NN1213, long-acting amylin analog
Storage & Handling
Store the lyophilized peptide below freezing (−80°C for the longest terms, −20°C otherwise). Reconstituted solution is aliquoted and held frozen to limit degradation.
References
- Kruse T, et al. Development of Cagrilintide, a long-acting amylin analogue. J Med Chem. 2021.
- Garvey WT, et al. Coadministered cagrilintide and semaglutide in adults with overweight or obesity. N Engl J Med. 2025.
✦Every vial ships with third-party HPLC verification; certificates of analysis are available on request.
Continue Exploring
