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RESEARCH, REFINED.
The details
Considered compounds. Documented standards.Explore our standard
RESEARCH, REFINED.Metabolic research
5-Amino 1MQ
50 mg / $75.00
5-Amino-1MQ is a small-molecule methylquinolinium derivative — not a peptide — supplied as the iodide salt.
Available formats
1
Availability and final pricing are checked at checkout.
Product documentationFor laboratory research use only. Not for human consumption.
A closer look
The details
behind the compound.
Overview
5-Amino-1MQ is a small-molecule methylquinolinium derivative — not a peptide — supplied as the iodide salt. It was rationally designed at the University of Texas Medical Branch as a membrane-permeable, selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT).
It is a focused reference for metabolic laboratory work, studied for its interaction with NNMT and downstream NAD-related pathways.
- Molecular formula
- C₁₀H₁₁IN₂ (iodide salt)
- Molecular weight
- 286.11 g/mol
- CAS number
- 42464-96-0
Laboratory documentation
A laboratory report is not available in the current product record for this format.
Research references
Neelakantan H, et al. Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase. J Med Chem. 2017.
Neelakantan H, et al. Selective and membrane-permeable small molecule inhibitors of NNMT reverse high-fat-diet-induced obesity in mice. Biochem Pharmacol. 2018.
Storage & handling
Store the powder at −20°C (or 4°C short-term), protected from light and moisture. Prepared solutions are best held frozen. As a small molecule, it is not subject to peptide freeze-thaw sensitivity.
